ISBN: 978-80-244-5763-5 | ISBN online: 978-80-244-5764-2 | DOI: 10.5507/lf.20.24457635

Bioelektrochemie

Jan Vacek, Veronika Ostatná

Electrochemical methods play an important role in fundamental as well as applied physical and chemical research, and they are nowadays widely used for analytical purposes, especially in the development of new sensors and in miniaturized laboratory technology, working both in stationary- and flow-through mode. Since the second half of the 20^th century, electrochemical approaches have been fully applied (among other areas) in biochemical and biophysical research, which led to the emergence of a new discipline called bioelectrochemistry. This book aims to inform readers about its fundamental aspects, as well as frequently used electrochemical methods and electrodes for the research of biologically active substances. Attention will be paid to both low-molecular-weight substances and macromolecular systems. In addition to research focused on the analysis of the redox properties, reactivity, or stability of biomolecules, dynamic processes associated with intermolecular interactions, transport phenomena and interactions of molecules with solid surfaces and with immobilized membranes will be described here. Attention will be paid to the electrochemical activity of biopolymers (nucleic acids, proteins/peptides and polysaccharides), and part of the book will also focus on the electrochemistry of highly complex cellular systems. Besides in vitro electrochemistry, in vivo applications are described and new possibilities opened up by electrochemical imaging methods, and the labeling of target molecules with redox-active tags is also highlighted. The book covers basic principles of bioelectrocatalysis, photobioelectrochemistry, electrochemiluminiscence, supramolecular electrochemistry, and the application of electrochemical sensors and microarrays. Electrochemistry at the interface between two immiscible electrolytes is also described. The authors do not claim to provide a comprehensive overview of current knowledge. On the contrary, the book focuses on selected areas of interest and subjects the above-mentioned research fields to discussion and critical evaluation.

1. edition, Published: 2020, online: 2020, publisher: Univerzita Palackého v Olomouci, Křížkovského 8, 771 47 Olomouc