ISBN online: 978-80-244-6177-9 | DOI: 10.5507/lf.22.24461779

Vybrané metody forenzní genetiky

Jiří Drábek (Ed.)

The methodological book "Selected Methods of Forensic Genetics" is intended for laboratory technicians at the Criminalistic Institute of Prague (KÚP), Department of Criminalistic Expertise (OKTE), and other laboratories dealing with genetic methods with potential application in criminalistics. It will also be useful for students of bachelor, master, and doctoral programmes of science faculties.
The book does not aim to provide an overview of the current state of methods development in the field of forensic genetics. The aim of our 11-member author team is to provide readers with only those methods that we ourselves have implemented and validated in our laboratories.
The introductory, theoretical chapter is followed by five method chapters: DNA profiling by STR locus analysis, identification of an unknown animal species, mtDNA sequencing using massively parallel sequencing, and two methods of methylation detection for biological age determination: pyrosequencing with a commercial kit and massively parallel sequencing with a laboratory-developed method.
Before each method chapter, the principles of the method are described, and the book is illustrated with pictures and diagrams. Each chapter is followed by tips for solving potential problems. The book promotes best laboratory practices to increase the reliability of forensic laboratory testing.

1. edition, online: 2022, publisher: Univerzita Palackého v Olomouci, Křížkovského 8, 771 47 Olomouc